Our research interests lie at the interface of medicine and engineering. Ongoing collaborative efforts with clinicians, engineers, physical scientists, and biologists have led to the design of new strategies that have advanced the development of engineered living tissues, implantable devices, and artificial organs, as well as cell-based therapies, which have helped to define the evolving field of Regenerative Medicine. Our laboratory has received more than $25 million in federal funding from the National Institutes of Health and the National Science Foundation, as well as support from the American Heart Association and the Juvenile Diabetes Research Foundation. Nearly two dozen patents have been issued or filed and have been licensed for improving the care of patients.
We are inspired by Nature. In the twenty-first century, we are witnessing a remarkable convergence of our synthetic and physical technologies with the world of molecular biology, which will provide unprecedented opportunities for the creation of novel, functional biomolecules. Biological systems display architectural complexity with hierarchical order at length scales greater than can be currently attained with synthetic systems. The complex structures of biology are formed from the self-assembly of molecular components, which is mediated through specific supramolecular interactions that are programmed into their molecular structure.